Calpain S1 antibody (AA 84-268)

Catalog No. ABIN5540248

The Mouse Monoclonal anti-Calpain S1 antibody (Clone AT1D11) (ABIN5540248) specifically detects Calpain S1 in WB, IF, ICC, FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for Calpain S1 antibody (AA 84-268) (ABIN5540248)

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain S1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: AT1D11

Product Details anti-Calpain S1 Antibody

Binding Specificity: AA 84-268

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human CAPNS1 (84-268aa) purified from E. coli.

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Calpain S1

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Alternative Name: capns1

Background: CAPNS1, also known as Calpain small subunit 1, are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Two transcript variants encoding the same protein have been identified for this gene.

UniProt: P04632

Pathways: Apoptosis