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EPS15 antibody (pTyr849)
EPS15
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EPS15 Antibody
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Target
See all EPS15 Antibodies
EPS15
(Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
Binding Specificity
All epitopes for EPS15 antibodies
pTyr849
Reactivity
All reactivities for EPS15 antibodies
Human, Mouse, Rat
Host
All hosts for EPS15 antibodies
Rabbit
Clonality
All clonalities for EPS15 antibodies
Polyclonal
Conjugate
All conjugates for EPS15 antibodies
This EPS15 antibody is un-conjugated
Application
All applications for EPS15 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous levels of EPS15 only when phosphorylated at tyrosine 849.
Purification
Affinity chromatography using epitope-specific peptide
Immunogen
Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15 (KLH-conjugated)
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Alternatives
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Application Details
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Application Notes
Western blot: 1:500~1:1000.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target Details for EPS15
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Target
EPS15
(Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
Alternative Name
af1p,eps15 (EPS15 Products )
Synonyms
AF-1P antibody, AF1P antibody, MLLT5 antibody, CG16932 antibody, Dmel\\CG16932 antibody, EH1 antibody, EPS-15 antibody, Eps15 antibody, anon-WO0118547.85 antibody, eps-15 antibody, eps15 antibody, i31 antibody, 2410112D09Rik antibody, RGD1307641 antibody, epidermal growth factor receptor pathway substrate 15 antibody, Epidermal growth factor receptor pathway substrate clone 15 antibody, hypothetical protein antibody, EPS15 antibody, Eps-15 antibody, eps15 antibody, Eps15 antibody, PGTG_06574 antibody
Background
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
UniProt
P42566
Pathways
EGFR Signaling Pathway , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development , EGFR Downregulation
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