Decorin antibody

Catalog No. ABIN264841

Product Details anti-Decorin Antibody

Target: Decorin (DCN)

Reactivity: Human, Mouse, Rat, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects ~22 kDa protein representing the Decorin fragment generated by digestion of Decorin by MMP-3.

Purification: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 130 of human Decorin.

Application Details

Application Notes: Western Blot (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 25 % Glycerol, 0,5 % BSA and 0.01 % Thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: Decorin (DCN Products)

Synonyms: CSCD antibody, DSPG2 antibody, PG40 antibody, PGII antibody, PGS2 antibody, SLRR1B antibody, DC antibody, mDcn antibody, cscd antibody, dspg2 antibody, pg40 antibody, pgii antibody, pgs2 antibody, slrr1b antibody, decorin antibody, decorin L homeolog antibody, DCN antibody, Dcn antibody, dcn.L antibody, dcn antibody

Background: Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q and epidermal growth factor receptor (EGFR9. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B

Gene ID: 1634

NCBI Accession: NP_001911

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process