CCR4 antibody (2nd Extracellular Domain)

Catalog No. ABIN302479

Product Details anti-CCR4 Antibody

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Binding Specificity: 2nd Extracellular Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects C-C Chemokine Receptor 4 (CCR4) at 2nd extracellular domain.

Purification: Immunoaffinity Chromatography

Immunogen: CCR4 antibody was raised against synthetic 18 amino acid peptide from 2nd extracellular domain of Human CCR4.

Application Details

Application Notes: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CD194 / CCR4 (CCR4 Products)

Synonyms: CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody

Background: CCR4, a Chemokine Receptor, mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5

Gene ID: 1233

NCBI Accession: NP_005499

UniProt: P51679