IFT88 antibody (C-Term)

Catalog No. ABIN374643

Product Details anti-IFT88 Antibody

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This IFT88 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-KKRIDEDDFA DEE

Specificity: This antibody is expected to recognize both reported isoforms (NP_783195.2, NP_006522.2).

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, MOuse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C-Terminus of the protein sequence (NP_783195.2, NP_006522.2). Genename: IFT88

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 1 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-IFT88 antibody (ABIN374643)

Madrigal-Matute, Fernandez-Garcia, Gomez-Guerrero, Lopez-Franco, Muñoz-Garcia, Egido, Blanco-Colio, Martin-Ventura: "HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis." in: Cardiovascular research, Vol. 95, Issue 1, pp. 116-23, (2012) (PubMed).

Schachner, Golderer, Sarg, Lindner, Bonaros, Mikuz, Laufer, Werner: "The amounts of alpha 1 antitrypsin protein are reduced in the vascular wall of the acutely dissected human ascending aorta." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 37, Issue 3, pp. 684-90, (2011) (PubMed).

Jiang, Chiou, Wang, Chien, Ho, Tsai, Lin, Tsai, Li: "Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse." in: Human molecular genetics, Vol. 18, Issue 9, pp. 1566-77, (2009) (PubMed).

Patzak, Lai, Fähling, Sendeski, Martinka, Persson, Persson: "Adenosine enhances long term the contractile response to angiotensin II in afferent arterioles." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 293, Issue 6, pp. R2232-42, (2008) (PubMed).

Target Details for IFT88

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Alternative Name: IFT88 (IFT88 Products)

Synonyms: 146590_s_at antibody, CG12548 antibody, CG14465 antibody, CG15190 antibody, CG4137 antibody, Dmel\\CG12548 antibody, IFT88 antibody, NOMPB antibody, OSM-5 antibody, Tg737 antibody, nomp antibody, osm-5 antibody, AW552028 antibody, Tg737Rpw antibody, TgN737Rpw antibody, Ttc10 antibody, flexo antibody, fxo antibody, orpk antibody, polaris antibody, D13S1056E antibody, DAF19 antibody, TG737 antibody, TTC10 antibody, hTg737 antibody, intraflagellar transport 88 antibody, intraflagellar transport 88 homolog antibody, intraflagellar transport protein 88 homolog antibody, no mechanoreceptor potential B antibody, IFT88 antibody, ift88 antibody, LOC100518926 antibody, LOC100640298 antibody, LOC100646898 antibody, nompB antibody, Ift88 antibody

Background: TTC10 is a member of the tetratrico peptide repeat (TPR) family. Mutations in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, TG737, TPR repeat protein 10, TTC10, Tetratricopeptide repeat protein 10

Gene ID: 8100

NCBI Accession: NP_006522

UniProt: Q13099

Pathways: Hedgehog Signaling, Sensory Perception of Sound