PPP3CB antibody

Catalog No. ABIN497960

Product Details anti-PPP3CB Antibody

Target: PPP3CB (Protein Phosphatase 3, Catalytic Subunit, beta Isozyme (PPP3CB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes PPP3CB/CALNA2 (34-198).

Cross-Reactivity (Details): Species reactivity (expected):Chicken (96 %), Rabbit (99 %), Rat (99 %), Xenopus laevis (83 %), Bovine (99 %), Xenopus tropicalis (83 %).
Species reactivity (tested):Human, Mouse

Purification: Antigen-Affinity Chromatography

Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 228 of PPP3CB

Application Details

Application Notes: Western blot: 1/1000-1/10000. Positive Controls: Molt-4. Immunohistochemistry on Formalin-Fixed Paraffin-Embedded Sections: 1/100-1/500. Antigen retrieval using heat mediated 10 mM Citrate buffer or Tris-EDTA buffer PH8.0 isSuggested.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) and 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for PPP3CB

Target: PPP3CB (Protein Phosphatase 3, Catalytic Subunit, beta Isozyme (PPP3CB))

Alternative Name: PPP3CB / CALNA2 (PPP3CB Products)

Synonyms: 1110063J16Rik antibody, Calnb antibody, CnAbeta antibody, Cnab antibody, CALNA2 antibody, CALNB antibody, CNA2 antibody, PP2Bbeta antibody, Calna2 antibody, protein phosphatase 3 catalytic subunit beta antibody, protein phosphatase 3, catalytic subunit, beta isoform antibody, PPP3CB antibody, Ppp3cb antibody

Background: PPP3CB (protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform) is a subunit of a calcium dependent, calmodulin stimulated serine/threonine phosphatase. PPP3CB may have a role in the calmodulin activation of calcineurin.Synonyms: CALNB, CAM-PRP catalytic subunit, CNA2, Calmodulin-dependent calcineurin A subunit beta isoform, Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, protein phosphatase 2B catalytic subunit beta

Molecular Weight: 59 kDa

Gene ID: 5532, 9606

UniProt: P16298

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Regulation of Leukocyte Mediated Immunity, VEGF Signaling, BCR Signaling