POU2F1 antibody (Internal Region)

Catalog No. ABIN569583

Product Details anti-POU2F1 Antibody

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Pig, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This POU2F1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-NVQSKSNEES GDSQQ

Specificity: Recognizes POU2F1 / OCT1

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Synthetic peptide corresponding to the internal region (near N Terminus) of Human POU2F1 (NP_002688.2). Genename: POU2F1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POU2F1

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Alternative Name: POU2F1 / OCT1 (POU2F1 Products)

Synonyms: OCT1 antibody, OTF1 antibody, oct-1B antibody, POU2F1 antibody, 2810482H01Rik antibody, NF-A1 antibody, Oct-1 antibody, Oct1 antibody, Otf-1 antibody, Otf1 antibody, chOCT-1 antibody, oct-1 antibody, oct1 antibody, pou2f1r antibody, fc07d06 antibody, wu:fc07d06 antibody, zgc:158360 antibody, POU class 2 homeobox 1 antibody, POU domain, class 2, transcription factor 1 antibody, POU class 2 homeobox 1 S homeolog antibody, POU class 2 homeobox 1b antibody, POU2F1 antibody, Pou2f1 antibody, pou2f1.S antibody, pou2f1b antibody

Background: Octamer transcrIPPtional factor 1 (Oct-1) is a 90 kDa transcrIPPtion factor that binds to the octamer motif ATTTGCAT. This ubiquitous regulatory element is most conspicuous in B cells, where it is found in every immunoglobulin (Ig) promoter and in most Ig enhancers. In addition, Oct-1 binding also activates the promoters of the genes for some small nuclear RNAs (snRNA) and for histone H2B. Oct-1 protein is expressed in multIPPle tissues although some Oct-1 isoforms appear to be tissue specific and the homologous Oct-2 appears to be restricted in expression to B-cells. At least in B-cells, the Oct proteins bind to DNA together with another protein transcrIPPtion factor, octamer binding factor-1 (OBF-1), to form a ternary complex.Synonyms: NF-A1, OTF1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Otf-1, POU domain class 2 transcription factor 1

Gene ID: 5451

NCBI Accession: NP_002688

UniProt: P14859