This antibody detects OGFOD1 at C-term. OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist, this antibody will only detect the larger isform.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse
Purification
Affinity chromatography purified via peptide column
Immunogen
18 amino acid peptide near the carboxy terminus of human OGFOD1
tpa1 antibody, MGC145343 antibody, D63 antibody, wu:fc33b08 antibody, zgc:66379 antibody, TPA1 antibody, 4930415J21Rik antibody, AA387199 antibody, AA939912 antibody, AW061076 antibody, mKIAA1612 antibody, RGD1308848 antibody, 2-oxoglutarate and iron dependent oxygenase domain containing 1 antibody, 2-oxoglutarate and iron-dependent oxygenase domain containing 1 antibody, 2-oxoglutarate and iron dependent oxygenase domain containing 1 L homeolog antibody, OGFOD1 antibody, ogfod1 antibody, ogfod1.L antibody, Ogfod1 antibody
Background
OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.Synonyms: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, FLJ10826, KIAA1612, TPA1, Termination and polyadenylation 1 homolog