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AIFM3 antibody (N-Term)

AIFM3 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499241
  • Target See all AIFM3 Antibodies
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 14
    • 1
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIFM3 antibody is un-conjugated
    Application
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to AIFM3.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    AIFM3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human AIFM3.
    Isotype
    IgG
    Top Product
    Discover our top product AIFM3 Primary Antibody
  • Application Notes
    ELISA. Western Blot: AIFM3 antibody can be used for the detection of AIFM3 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Abstract
    AIFM3 Products
    Synonyms
    nfrl-A antibody, MGC84340 antibody, AIFM3 antibody, LOC100150876 antibody, 2810401C16Rik antibody, AI840249 antibody, Aifl antibody, RGD1306028 antibody, AIFL antibody, apoptosis inducing factor, mitochondria associated 3 L homeolog antibody, apoptosis inducing factor, mitochondria associated 3 antibody, apoptosis-inducing factor, mitochondrion-associated 3 antibody, aifm3.L antibody, AIFM3 antibody, aifm3 antibody, Aifm3 antibody
    Background
    Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.Synonyms: AIFL, Apoptosis-inducing factor 3
    Gene ID
    150209
    UniProt
    Q96NN9
    Pathways
    Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
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