Recombinant Netrin 1 antibody
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- Target See all Netrin 1 (NTN1) Antibodies
- Netrin 1 (NTN1)
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human, Mouse
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Host
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Human
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Clonality
- Monoclonal
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Conjugate
- This Netrin 1 antibody is un-conjugated
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Application
- ELISA, Functional Studies (Func)
- Specificity
- Recognizes human and mouse Netrin-1.
- Cross-Reactivity
- Human, Mouse (Murine)
- Cross-Reactivity (Details)
- Does not recognize Netrin-4.
- Purity
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant human netrin-1.
- Clone
- H4
- Isotype
- IgG2
- Top Product
- Discover our top product NTN1 Primary Antibody
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- Comment
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anti-Netrin-1 (human), mAb (rec.) (blocking) (H4) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol.
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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- Target
- Netrin 1 (NTN1)
- Alternative Name
- Netrin-1 (NTN1 Products)
- Synonyms
- ntn1-A antibody, Netrin-1 antibody, NTN1 antibody, unc-6 antibody, MGC147073 antibody, NTN1L antibody, AI561871 antibody, BC019633 antibody, netrin-1 antibody, netrin 1 L homeolog antibody, netrin 1 antibody, ntn1.L antibody, NTN1 antibody, ntn1 antibody, Ntn1 antibody
- Background
- Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.
- UniProt
- O95631
- Pathways
- Regulation of Cell Size
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