Serotonin Receptor 3A antibody (AA 24-157)

Catalog No. ABIN5611116

The Mouse Monoclonal anti-Serotonin Receptor 3A antibody has been validated for ELISA, IHC, ICC and FACS. It is suitable to detect Serotonin Receptor 3A in samples from Human.

Quick Overview for Serotonin Receptor 3A antibody (AA 24-157) (ABIN5611116)

Target: Serotonin Receptor 3A (HTR3A)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3B11C10

Product Details anti-Serotonin Receptor 3A Antibody

Binding Specificity: AA 24-157

Purpose: HTR3A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HTR3A (AA: 24-157) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: HTR3A

Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 55.3 kDa

Gene ID: 3359

UniProt: P46098

Pathways: Synaptic Membrane