GRIK2 antibody (C-Term)

Catalog No. ABIN6261991

The Rabbit Polyclonal anti-GRIK2 antibody (ABIN6261991) specifically detects GRIK2 in WB, IHC, IF and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for GRIK2 antibody (C-Term) (ABIN6261991)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GRIK2 Antibody

Binding Specificity: C-Term

Purpose: GluR6 Antibody

Specificity: GluR6 Antibody detects endogenous levels of total GluR6.

Predicted Reactivity: Pig,Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GluR6, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GluR6

Background:

Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.

Gene: GRM6

Molecular Weight: 95 kDa

Gene ID: 2916

UniProt: O15303

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity