TSHR, B Chain antibody (AA 515-538)

Catalog No. ABIN5647201

Product Details anti-TSHR, B Chain Antibody

Target: TSHR, B Chain (Thyroid Stimulating Hormone Receptor, B Chain (TSHR, B Chain))

Binding Specificity: AA 515-538

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSHR, B Chain antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: Amino acids 515-538 (ITLERWYAITFAMRLDRKIRLRHA) from the beta subunit of the human protein were used as the immunogen for the TSH Receptor antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TSH Receptor antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the TSH Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for TSHR, B Chain

Target: TSHR, B Chain (Thyroid Stimulating Hormone Receptor, B Chain (TSHR, B Chain))

Alternative Name: Thyroid Stimulating Hormone Receptor / TSHR (beta chain) (TSHR, B Chain Products)

Background: TSHR (Thyroid-Stimulating Hormone Receptor), also called LGR3, is mapped to 14q31.1. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: P16473