PKD2 antibody (AA 556-590)
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- Target See all PKD2 Antibodies
- PKD2 (Protein Kinase D2 (PKD2))
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Binding Specificity
- AA 556-590
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PKD2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity (Details)
- Expected species reactivity: Rat
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 556-590 from the human protein was used as the immunogen for the PKD2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PKD2 Primary Antibody
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- Application Notes
- Western blot: 1:500-2000
- Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the PKD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- PKD2 (Protein Kinase D2 (PKD2))
- Alternative Name
- PKD2 / Protein kinase D2 (PKD2 Products)
- Synonyms
- PKD2 antibody, nPKC-D2 antibody, AI325941 antibody, RGD1308054 antibody, PRKD2 antibody, protein kinase D2 antibody, serine/threonine-protein kinase D2 antibody, PRKD2 antibody, Prkd2 antibody, LOC100407181 antibody
- Background
- Protein kinase D2 is a serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion.
- Gene ID
- 25865
- UniProt
- Q9BZL6
- Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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