ALDH1A2 antibody

Catalog No. ABIN5647735

Product Details anti-ALDH1A2 Antibody

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: Amino acids M1-A110 from the human protein were used as the immunogen for the ALDH1A2 antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Prior to reconstitution, store at 4°C. After reconstitution, the ALDH1A2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2 (ALDH1A2 Products)

Synonyms: Raldh-2 antibody, RALDH(II) antibody, RALDH2 antibody, RALDH2-T antibody, fb50h01 antibody, raldh2 antibody, AV116159 antibody, Aldh1a7 antibody, Raldh1 antibody, Raldh2 antibody, aldehyde dehydrogenase 1 family, member A2 antibody, aldehyde dehydrogenase 1 family member A2 antibody, aldehyde dehydrogenase family 1, subfamily A2 antibody, Aldh1a2 antibody, ALDH1A2 antibody, aldh1a2 antibody

Background: Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway