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Recombinant CD11b antibody

ITGAM Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 107 unconjugated Recombinant Antibody
Catalog No. ABIN5668175
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 258
    • 168
    • 62
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Human
    Host
    • 136
    • 105
    • 103
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 250
    • 96
    • 1
    Monoclonal
    Conjugate
    • 119
    • 37
    • 29
    • 26
    • 20
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is un-conjugated
    Application
    • 259
    • 84
    • 76
    • 72
    • 59
    • 40
    • 35
    • 27
    • 22
    • 20
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA
    Specificity
    This antibody binds to the MIDAS face of the A domain from integrin CD11b.
    Characteristics

    OriginalSpeciesName: Mouse

    OriginalFormat: IgG1

    Purification
    Purified antibody.
    Immunogen
    Wild type (WT) recombinant CD11b.
    Clone
    107
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    he antibody binds specifically to integrin a-M, a protein subunit of the a-M- ß-2 Molecule, which is expressed on the surface of leukocytes. Integrin a-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    Integrin alpha-M (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    CD11b, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, Neutrophil adherence receptor, complement receptor 3
    UniProt
    P11215
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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