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Recombinant CD40 antibody

CD40 Reactivity: Human FACS, IHC, IP, Act Host: Mouse Monoclonal G28-5 unconjugated Recombinant Antibody

Catalog No. ABIN5668237

Datasheet as PDF

Target See all CD40 Antibodies

CD40

Antibody Type

Recombinant Antibody
Reactivity
178

92

20

19

6

6

4

4

4

4

2

2

2

2

2

1
Human
Host
98

96

39

3

1

1
Mouse
Compatible Secondaries
Clonality
143

88

5
Monoclonal
Conjugate
114

20

19

18

10

6

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is un-conjugated
Application
135

91

61

48

28

23

19

17

16

14

13

13

5

4

4

3

3

3

3

3

2

2

2

2

2

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Activation (Act)

Specificity

48 kD Type I glycoprotein, a member of the TNFR superfamily primarily expressed on normal or malignant B cells or B cell lines, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.

Characteristics

OriginalSpeciesName: Mouse
OriginalFormat: IgG1

Purification

Purified antibody.

Immunogen

Human erythrocyte-rosette-negative tonsillar lymphocytes.

Clone

G28-5

Isotype

IgG1 kappa

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CD40 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 4E1B9 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivity: Human FACS, ELISA, IHC, StM, Coat Host: Mouse Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivity: Human FACS, IHC, St Host: Mouse Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a FITC

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IP, Act Host: Rabbit Chimeric G28-5 unconjugated Recombinant Antibody

Application Notes

This antibody detects CD40 by immunostaining. The original mouse IgG1 format was shown to stimular B-cells (Bishop 2012 and references therein).

Restrictions

For Research Use only
Buffer

PBS with 0.02 % Proclin 300.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target

CD40

Alternative Name

CD40 (CD40 Products)

Synonyms

Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody

Background

TNFRS5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor CDw40, CD154R

UniProt

P25942

Pathways

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints