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MP2K7 antibody (C-Term)

LOC108911176 Reactivity: Mouse, Rabbit, Rat, Cow, Sheep, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5671373
  • Target See all MP2K7 (LOC108911176) products
    MP2K7 (LOC108911176) (Dual Specificity Mitogen-Activated Protein Kinase Kinase 7-Like (LOC108911176))
    Binding Specificity
    C-Term
    Reactivity
    Mouse, Rabbit, Rat, Cow, Sheep, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Western Blotting (WB)
    Sequence
    KDCLTKDHRK RPKYNKLLEH SFIKRYETLE VDVASWFKDV MAKTESPRTS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against MP2K7. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MP2K7 (LOC108911176) (Dual Specificity Mitogen-Activated Protein Kinase Kinase 7-Like (LOC108911176))
    Alternative Name
    MP2K7 (LOC108911176 Products)
    Background
    The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

    Alias Symbols: MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4,

    Protein Interaction Partner: MAPK8, MAP3K3, MAP3K2, UBC, FBXO6, MAP3K11, MAPK8IP1, LPXN, VRK2, RPL30, MAPK9, HSP90AA1, ATF4, JUN, WDR6, BCL10, MAP2K4, MAPK1, LRRK2, MAP3K4, MAP3K1, MYC, ELAVL1, ALK, DUSP22, DUSP19, MAPK8IP3, CNKSR1, ZAK, TRIB1, MAPK8IP2, GADD45B, CFLAR, MAP2K7, MAP3K

    Protein Size: 462
    Gene ID
    5609
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