Ryncolin-1-Like antibody (Middle Region)

Catalog No. ABIN5671385

Product Details anti-Ryncolin-1-Like Antibody

Target: Ryncolin-1-Like (LOC108969966)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ryncolin-1-Like antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PDSPSSVGRP SSDPGLSPTQ PCPEGSGDCR KQCEPDYYLD EAGRCTACVS

Characteristics: This is a rabbit polyclonal antibody against TNR8. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TNR8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ryncolin-1-Like

Target: Ryncolin-1-Like (LOC108969966)

Alternative Name: TNR8 (LOC108969966 Products)

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alias Symbols: TNFRSF8, CD30, D1S166E,

Protein Interaction Partner: UBC, Traf2, Traf1, TRAF5, TRAF3, TNFRSF8, BCL6, TDP2, TNFSF8, ALK, TRAIP,

Protein Size: 483

Gene ID: 943

NCBI Accession: NP_001268359