MICU1 antibody (N-Term)

Catalog No. ABIN5672990

The Rabbit Polyclonal anti-MICU1 antibody (ABIN5672990) specifically detects MICU1 in WB. The antibody is reactive with Human samples.

Quick Overview for MICU1 antibody (N-Term) (ABIN5672990)

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICU1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MICU1 Antibody

Binding Specificity: N-Term

Sequence: CVDNLKSDIG DKGKNKDEGD VCNHEKKTAD LAPHPEEKKK KRSGFRDRKV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CBARA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Alternative Name: CBARA1

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Alias Symbols: CALC, EFHA3, MPXPS, CBARA1

Protein Size: 403

Gene ID: 10367

NCBI Accession: NM_001195518, NP_001182447