Calretinin, no cross-reaction with Calbindin and Calmodulin
Cross-Reactivity (Details)
Human, Rat
Characteristics
The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90 % of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin, no cross-reaction with Calbindin and Calmodulin.
Improvement of staining with Unmasking Fluid G or Unmasking Fluid C ,Cerebral cortex, pleural mesothelioma,IHC(C, P), Immunoblotting,60 min at RT,(liquid conc.) 1:40-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for 200-500 immunohistochemical tests (100 μL working solution / test)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.