CXCL7 antibody

Catalog No. ABIN5688705

Product Details anti-CXCL7 Antibody

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: This IgG1/K antibody was purified from a Protein A chromatography column.

Immunogen: The monoclonal antibody was produced in BALB/c mice using recombinant human NAP-2 as the immunizing antigen.

Clone: G6_5C7-3

Application Details

Application Notes: ELISA:

In a sandwich ELISA (assuming 100 μ,L/well), a concentration of 2.0-4.0 μ,g/mL of this antibody will detect at least 500 pg/mL of recombinant human NAP-2 when used with our biotinylated antigen affinity purified anti-human NAP-2 (XP-5244Bt) as the detection antibody at a concentration of approximately 0.5-1.0 μ,g/mL.

Western blot:

To detect hNAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.5-1.0 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNAP-2 is 0.5-1.0 ng/lane, under reducing or non-reducing conditions.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C,-20 °C

Storage Comment: NAP-2 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4°C when reconstituted.

Target Details for CXCL7

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Alternative Name: NAP-2 (PPBP Products)

Synonyms: 2400003M24Rik antibody, AI854500 antibody, CTAP3 antibody, CTAPIII antibody, Cxcl7 antibody, LA-PF4 antibody, LDGF antibody, MDGF antibody, NAP-2 antibody, NAP-2-L1 antibody, Scyb7 antibody, TGB antibody, TGB1 antibody, THBGB1 antibody, b-TG1 antibody, beta-TG antibody, B-TG1 antibody, Beta-TG antibody, CTAP-III antibody, CXCL7 antibody, PBP antibody, SCYB7 antibody, TC1 antibody, TC2 antibody, THBGB antibody, Nap-2 antibody, CTAPIII/NAP-2 antibody, Platelet basic protein antibody, pro-platelet basic protein antibody, scyb7 antibody, Ppbp antibody, PPBP antibody

Background: NAP2 is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Gene ID: 5473

UniProt: P02775