PPARG antibody (AA 50-54)

Catalog No. ABIN5689403

The Rabbit Polyclonal anti-PPARG antibody (ABIN5689403) specifically detects PPARG in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for PPARG antibody (AA 50-54) (ABIN5689403)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPARG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPARG Antibody

Binding Specificity: AA 50-54

Specificity: This antibody detects endogenous levels of total PPARγ, protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: PPARgamma antibody was raised against a peptide sequence around aa.50~54 (L-S-V-M-E) derived from Human PPARγ,.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Alternative Name: PPARgamma

Background: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.

Molecular Weight: 53 57 kDa

Gene ID: 5468

NCBI Accession: NP_005028

UniProt: P37231

Pathways: MAPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation