MAP2K4 antibody (AA 78-82)

Catalog No. ABIN5689476

This Rabbit Polyclonal antibody specifically detects MAP2K4 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAP2K4 antibody (AA 78-82) (ABIN5689476)

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAP2K4 Antibody

Binding Specificity: AA 78-82

Specificity: This antibody detects endogenous level of total SEK1/MKK4 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: SEK1/MKK4 (Ab-80) antibody was raised against a peptide sequence around aa. 78~82 (T-H-S-I-E) derived from Human SEK1/MKK4.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: SEK1 / MKK4

Background: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

Molecular Weight: 44 kDa

Gene ID: 6416

NCBI Accession: NP_003001

UniProt: P45985

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling