GSK3 alpha antibody (AA 19-23)

Catalog No. ABIN5689508

This anti-GSK3 alpha antibody is a Rabbit Polyclonal antibody detecting GSK3 alpha in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for GSK3 alpha antibody (AA 19-23) (ABIN5689508)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GSK3 alpha Antibody

Binding Specificity: AA 19-23

Specificity: This antibody detects endogenous level of total GSK3α, protein. and does not detect GSK-3β, protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: GSK3a (Ab-21) antibody was raised against a peptide sequence around aa.19~23 (T-S-S-F-A) derived from Human GSK3α,.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3a

Background: Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN

Molecular Weight: 51 kDa

Gene ID: 2931

NCBI Accession: NP_063937

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect