MMP 9 antibody (AA 260-310)

Catalog No. ABIN5690057

Product Details anti-MMP 9 Antibody

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Binding Specificity: AA 260-310

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: MMP9 antibody is human, mouse and rat reactive. At least three isoforms of MMP9 are known to exist, this antibody only recognizes the two longest isoforms.

Purification: MMP9 Antibody is affinity chromatography purified via peptide column.

Immunogen: MMP9 antibody was raised against a 16 amino acid peptide near the center of human MMP9.

The immunogen is located within amino acids 260 - 310 of MMP9 .

Isotype: IgG

Application Details

Application Notes: MMP9 antibody can be used for detection of MMP9 by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MMP9 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MMP9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for MMP 9

Target: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Alternative Name: MMP9 (MMP9 Products)

Synonyms: CLG4B antibody, GELB antibody, MANDP2 antibody, MMP-9 antibody, AW743869 antibody, B/MMP9 antibody, Clg4b antibody, pro-MMP-9 antibody, mmp-9 antibody, fgMMP-9 antibody, mmp9 antibody, ZFMMP-9 antibody, wu:fb02g06 antibody, wu:fb07b05 antibody, wu:fi98c09 antibody, wu:fj05a08 antibody, zgc:64165 antibody, clg4b antibody, gelb antibody, mandp2 antibody, matrix metallopeptidase 9 antibody, collagenase antibody, matrix metalloproteinase 9 antibody, matrix metallopeptidase 9 S homeolog antibody, MMP9 antibody, RB3913 antibody, BPSS0666 antibody, Sbal_3732 antibody, Bcer98_0486 antibody, Shew185_0630 antibody, Shal_3056 antibody, Sbal195_0657 antibody, Lbys_3550 antibody, Palpr_2084 antibody, Mmp9 antibody, mmp9 antibody, mmp9.S antibody

Background: The matrix metalloproteinase (MMP) family are a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases (1). MMP9 degrades type IV and V collagens (2) and studies suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow (3) and plays a role in tumor-associated tissue remodeling (4).

Molecular Weight: Predicted: 76 kDa

Observed: 73kDa

Gene ID: 4318

NCBI Accession: NP_004985

UniProt: P14780

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events