GPRASP1 antibody (AA 60-110)

Catalog No. ABIN5690247

Product Details anti-GPRASP1 Antibody

Target: GPRASP1 (G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1))

Binding Specificity: AA 60-110

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRASP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist, this antibody will detect both isoforms.

Purification: SKI2W antibody is affinity chromatography purified via peptide column.

Immunogen: SKI2W antibody was raised against a 16 amino acid peptide near the amino terminus of human SKI2W.

The immunogen is located within amino acids 60 - 110 of SKI2W.

Isotype: IgG

Application Details

Application Notes: SKI2W antibody can be used for detection of SKI2W by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SKI2W antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SKI2W antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for GPRASP1

Target: GPRASP1 (G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1))

Alternative Name: GPRASP1 (GPRASP1 Products)

Synonyms: pips antibody, 2210415K24Rik antibody, 3110031O14Rik antibody, C87852 antibody, GASP antibody, GASP1 antibody, GASP-1 antibody, G protein-coupled receptor associated sorting protein 1 antibody, Gprasp1 antibody, GPRASP1 antibody

Background: SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2). SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2). The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4).

Molecular Weight: Predicted: 113, 137 kDa

Observed: 135 kDa

Gene ID: 6499

NCBI Accession: NP_008860

UniProt: Q15477