TFPI antibody (AA 70-120)

Catalog No. ABIN5690286

Product Details anti-TFPI Antibody

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Binding Specificity: AA 70-120

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist, this antibody will detect both isoforms.

Purification: TFPI Antibody is affinity chromatography purified via peptide column.

Immunogen: TFPI antibody was raised against a 13 amino acid peptide near the amino terminus of human TFPI.

The immunogen is located within amino acids 70 - 120 of TFPI.

Isotype: IgG

Application Details

Application Notes: TFPI antibody can be used for detection of TFPI by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TFPI Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TFPI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TFPI

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Alternative Name: TFPI (TFPI Products)

Synonyms: EPI antibody, LACI antibody, TFI antibody, TFPI1 antibody, A630013F22Rik antibody, AW552122 antibody, TFPI antibody, si:dz44f8.1 antibody, tfpib antibody, wu:fb92g01 antibody, zgc:152844 antibody, zgc:158592 antibody, tissue factor pathway inhibitor antibody, tissue factor pathway inhibitor a antibody, TFPI antibody, Tfpi antibody, tfpia antibody

Background: TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).

Molecular Weight: Predicted: 33 kDa

Observed: 30 kDa

Gene ID: 7035

NCBI Accession: NP_006278

UniProt: P10646