TPMT antibody (AA 1-245)
-
- Target See all TPMT Antibodies
- TPMT (Thiopurine S-Methyltransferase (TPMT))
-
Binding Specificity
- AA 1-245
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TPMT antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
- Rabbit IgG polyclonal antibody for TPMT detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Immunogen
- E. coli-derived human TPMT recombinant protein (Position: M1-K245).
- Top Product
- Discover our top product TPMT Primary Antibody
-
-
- Application Notes
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
- Target
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- Alternative Name
- TPMT (TPMT Products)
- Synonyms
- MGC84277 antibody, AW106912 antibody, NHLRC1 antibody, thiopurine S-methyltransferase L homeolog antibody, thiopurine S-methyltransferase, tandem duplicate 2 antibody, thiopurine S-methyltransferase TpmT antibody, thiopurine S-methyltransferase antibody, Thiopurine S-methyltransferase antibody, thiopurine methyltransferase antibody, tpmt.L antibody, tpmt.2 antibody, tpmT antibody, MCA0794 antibody, Pnap_4948 antibody, Hhal_1383 antibody, TK90_1044 antibody, Slit_1144 antibody, Tint_0842 antibody, Fbal_3334 antibody, Celly_3188 antibody, Weevi_1737 antibody, Psefu_2696 antibody, Metme_3860 antibody, Tpmt antibody, TPMT antibody
- Background
-
Synonyms: Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT
Background: Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
- UniProt
- P51580
-