NPS antibody

Catalog No. ABIN5693247

Product Details anti-NPS Antibody

Target: NPS (Neuropeptide S (NPS))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPS antibody is un-conjugated

Application: Western Blotting (WB)

Brand: Picoband™

Sequence: SFRNGVGTGM KKTSFQRAKS

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human

Characteristics: Rabbit IgG polyclonal antibody for Neuropeptide S detection. Tested with WB in Human,Mouse,Rat.

Immunogen: A synthetic peptide corresponding to a sequence of human Neuropeptide S (SFRNGVGTGMKKTSFQRAKS).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for NPS

Target: NPS (Neuropeptide S (NPS))

Alternative Name: NPS (NPS Products)

Synonyms: ENSMUSG00000073804 antibody, neuropeptide S antibody, NPS antibody, Nps antibody

Background:

Synonyms: Neuropeptide S, NPS

Background: Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas. NPS binds specifically to a G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and appetite, induces wakefulness and hyperactivity, including hyper-sexuality, and plays a significant role in the extinction of conditioned fear.It has also been shown to significantly enhance dopamine activity in the mesolimbic pathway, and inhibits motility and increases permeability in neurocrine fashion acting through NO in the myenteric plexus in rats and humans.

UniProt: P0C0P6