FOXC1 antibody (Internal Region)

Catalog No. ABIN569579

Product Details anti-FOXC1 Antibody

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-DAVKDKEEKD RLH

Specificity: Recognizes FOXC1 (internal).

Cross-Reactivity (Details): Species reactivity (expected):Pig, Mouse.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Dynthetic peptide from an internal region of Human FOXC1 (NP_001444.2). Genename: FOXC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1 / FKHL7 / FREAC3 (FOXC1 Products)

Synonyms: ARA antibody, FKHL7 antibody, FREAC-3 antibody, FREAC3 antibody, IGDA antibody, IHG1 antibody, IRID1 antibody, RIEG3 antibody, FoxC1 antibody, fkhl7 antibody, freac-3 antibody, freac3 antibody, igda antibody, ihg1 antibody, irid1 antibody, rieg3 antibody, xfd-11 antibody, ara antibody, FOXC1 antibody, foxc1 antibody, Fkh1 antibody, Mf1 antibody, Mf4 antibody, ch antibody, fkh-1 antibody, frkhda antibody, CFKH-1 antibody, XFD-11 antibody, foxc1.2 antibody, id:ibd5079 antibody, forkhead box C1 antibody, forkhead box C1 S homeolog antibody, forkhead box C1 L homeolog antibody, Forkhead box protein C1 antibody, winged helix transcription factor XFD-11 antibody, forkhead box C1b antibody, FOXC1 antibody, Foxc1 antibody, foxc1.S antibody, foxc1 antibody, foxc1.L antibody, foxc1-A antibody, foxc1b antibody

Background: FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.Synonyms: FREAC-3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3

Molecular Weight: 56.8kDa (NP_001444.2).

Gene ID: 2296

NCBI Accession: NP_001444

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process