HLAG antibody

Catalog No. ABIN569693

The Mouse Monoclonal anti-HLAG antibody is suitable to detect HLAG in samples from Human. It has been validated for FACS, IP, IHC (fro), IF and EIA.

Quick Overview for HLAG antibody (ABIN569693)

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: MEM-G-9

Product Details anti-HLAG Antibody

Specificity: The antibody reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form.

Purification: Precipitation methods

Purity: > 95 % (by SDS-PAGE)

Immunogen: Recombinant human HLA-G refolded with beta2-microglobulin and peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Azide free phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4

Preservative: Azide free

Handling Advice: Dilute only prior to immediate use

Storage: 4 °C

Storage Comment: Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA Class I alpha G / HLA-G

Background: HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G

Gene ID: 3135

NCBI Accession: NP_002118

UniProt: P17693

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response