CD166 antibody

Catalog No. ABIN5697028

Product Details anti-CD166 Antibody

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD166 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: activated leukocyte cell adhesion molecule

Isotype: IgG

Application Details

Application Notes: WB :1:200-1:2000,IHC:1:20-1:200

Comment:

human liver tissue were subjected to SDS PAGE followed by western blot with FNab00280(ALCAM antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Alternative Name: ALCAM (ALCAM Products)

Synonyms: CD166 antibody, MEMD antibody, ALCAM antibody, BEN antibody, DM-GRASP antibody, JC7 antibody, SC1 antibody, AI853494 antibody, MuSC antibody, alcam antibody, cd166 antibody, memd antibody, fb53h09 antibody, fb80a10 antibody, nlcam antibody, si:ch211-190h2.4 antibody, wu:fb53h09 antibody, wu:fb80a10 antibody, wu:fc14b01 antibody, activated leukocyte cell adhesion molecule antibody, activated leukocyte cell adhesion molecule a antibody, activated leukocyte cell adhesion molecule L homeolog antibody, CD166 antigen homolog antibody, activated leukocyte cell adhesion molecule b antibody, ALCAM antibody, Alcam antibody, alcama antibody, alcam.L antibody, alcam antibody, cd166 antibody, alcamb antibody

Background: Synonyms:ALCAM, CD166, CD166 antigen, FLJ38514, MEMD Background:Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts(PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6(PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6(PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM(PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow(PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction(PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions(PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation(By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons(By similarity). Isoform 3: Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.

Molecular Weight: 65kDa,observed 110kDa

Gene ID: 214

UniProt: Q13740