ELL antibody
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- Target See all ELL Antibodies
- ELL (Elongation Factor RNA Polymerase II (ELL))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ELL antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- elongation factor RNA polymerase II
- Isotype
- IgG
- Top Product
- Discover our top product ELL Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab02740(ELL antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- ELL (Elongation Factor RNA Polymerase II (ELL))
- Alternative Name
- ELL (ELL Products)
- Synonyms
- wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody
- Background
- Synonyms:C19orf17 Background:Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription(PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
- Molecular Weight
- 68-80 kDa
- Gene ID
- 8178
- UniProt
- P55199
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