IPO13 antibody
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- Target See all IPO13 Antibodies
- IPO13 (Importin 13 (IPO13))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IPO13 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- importin 13
- Isotype
- IgG
- Top Product
- Discover our top product IPO13 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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human brain tissue were subjected to SDS PAGE followed by western blot with FNab04374(IPO13 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- IPO13 (Importin 13 (IPO13))
- Alternative Name
- IPO13 (IPO13 Products)
- Synonyms
- 3R23 antibody, CG 7212 antibody, CG7212 antibody, Dmel\\CG7212 antibody, Imp13 antibody, imp13 antibody, sd-5 antibody, DDBDRAFT_0205767 antibody, DDBDRAFT_0304414 antibody, DDB_0205767 antibody, DDB_0304414 antibody, DDBDRAFT_0191787 antibody, DDBDRAFT_0304413 antibody, DDB_0191787 antibody, DDB_0304413 antibody, IMP13 antibody, KAP13 antibody, LGL2 antibody, RANBP13 antibody, Kap13 antibody, Ranbp13 antibody, Lgl2 antibody, DKFZp459H088 antibody, cadmus antibody, importin 13 antibody, cdm antibody, IPO13 antibody, AFUA_5G08060 antibody, ANI_1_1340034 antibody, AOR_1_1272114 antibody, ipo13B antibody, ipo13A antibody, ipo13 antibody, Ipo13 antibody
- Background
- Synonyms:KIAA0724, RANBP13 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.
- Molecular Weight
- 97 kDa
- Gene ID
- 9670
- UniProt
- O94829
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
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