WTAP antibody
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- Target See all WTAP Antibodies
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WTAP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Immunogen
- Wilms tumor 1 associated protein
- Isotype
- IgG
- Top Product
- Discover our top product WTAP Primary Antibody
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- Application Notes
- WB:1:500-1:2000
- Comment
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09529(WTAP antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- Alternative Name
- WTAP (WTAP Products)
- Synonyms
- MGC75954 antibody, WTAP antibody, RGD1563824 antibody, wu:fi29a09 antibody, zgc:66202 antibody, 2810408K05Rik antibody, 9430038B09Rik antibody, WT1 associated protein antibody, Wilms tumor 1 associated protein antibody, wilms tumor 1 associated protein antibody, WT1 associated protein L homeolog antibody, Wilms tumour 1-associating protein antibody, wtap antibody, WTAP antibody, CpipJ_CPIJ006489 antibody, Wtap antibody, wtap.L antibody
- Background
- Synonyms:DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP Background:Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
- Molecular Weight
- 49kDa,Observed 55kDa
- Gene ID
- 9589
- UniProt
- Q15007
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