ZKSCAN3 antibody

Catalog No. ABIN5698798

Product Details anti-ZKSCAN3 Antibody

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Immunogen: zinc finger with KRAB and SCAN domains 3

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000,IF:1:10-1:100

Comment:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab09646(ZKSCAN3 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: 4°C for 12 months

Expiry Date: 12 months

Target Details for ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Alternative Name: ZKSCAN3 (ZKSCAN3 Products)

Synonyms: ZKSCAN3 antibody, ZNF306 antibody, ZF47 antibody, ZFP306 antibody, ZNF309 antibody, ZSCAN13 antibody, ZSCAN35 antibody, Zfp47 antibody, dJ874C20.1 antibody, dJ874C20.1. antibody, zfp-47 antibody, 2810435N07Rik antibody, AA408594 antibody, AI132359 antibody, Skz1 antibody, Zf47 antibody, Zfp-47 antibody, Zfp306 antibody, Zfp307 antibody, mszf35 antibody, zinc finger with KRAB and SCAN domains 3 antibody, ZKSCAN3 antibody, Zkscan3 antibody

Background: Synonyms:ZKSCAN3, dJ874C20.1, KIAA0426, ZF47, ZFP306 Background:Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Molecular Weight: 65kDa

Gene ID: 80317

UniProt: Q9BRR0