NrCAM antibody
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- Target See all NrCAM (NRCAM) Antibodies
- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NrCAM antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- neuronal cell adhesion molecule
- Isotype
- IgG
- Top Product
- Discover our top product NRCAM Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05852(NRCAM antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
- Alternative Name
- NRCAM (NRCAM Products)
- Synonyms
- CD56 antibody, MSK39 antibody, NCAM antibody, Bravo antibody, C030017F07Rik antibody, C130076O07Rik antibody, mKIAA0343 antibody, NRCAM antibody, si:dkey-240a12.1 antibody, Nr-CAM antibody, neural cell adhesion molecule 1 antibody, neuronal cell adhesion molecule antibody, neuronal cell adhesion molecule L homeolog antibody, neuronal cell adhesion molecule a antibody, NCAM1 antibody, NRCAM antibody, Nrcam antibody, nrcam.L antibody, nrcama antibody, nrcam antibody
- Background
- Synonyms:KIAA0343 Background:Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes, not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
- Molecular Weight
- 130-136 kDa
- Gene ID
- 4897
- UniProt
- Q92823
- Pathways
- Regulation of Cell Size
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