ULK1 antibody

Catalog No. ABIN5699097

Product Details anti-ULK1 Antibody

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogen: unc-51-like kinase 1 (C. elegans)

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:1000,IHC:1:50-1:500

Comment:

rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09251( ULK1 Antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Alternative Name: ULK1 (ULK1 Products)

Synonyms: ATG1 antibody, ATG1A antibody, UNC51 antibody, Unc51.1 antibody, hATG1 antibody, si:dkey-11o18.7 antibody, ulk1 antibody, ULK1 antibody, AU041434 antibody, mKIAA0722 antibody, zgc:195008 antibody, unc-51 like autophagy activating kinase 1 antibody, unc-51 like kinase 1 antibody, unc-51 like autophagy activating kinase 1a antibody, ULK1 antibody, Ulk1 antibody, ulk1b antibody, ulk1a antibody

Background: Synonyms:ATG1, FLJ38455, FLJ46475, KIAA0722, ULK1, Unc 51 like kinase 1, UNC51, Unc51.1 Background:ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

Molecular Weight: 150kDa

Gene ID: 8408

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy