TRIM6 antibody

Catalog No. ABIN5699858

Product Details anti-TRIM6 Antibody

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: tripartite motif-containing 6

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000,IHC:1:20-1:200

Comment:

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08991(TRIM6 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TRIM6

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Alternative Name: TRIM6 (TRIM6 Products)

Synonyms: TRIM6 antibody, DKFZP469D1621 antibody, RNF89 antibody, C430046K18Rik antibody, D7Ertd684e antibody, tripartite motif containing 6 antibody, tripartite motif-containing 6 antibody, TRIM6 antibody, Trim6 antibody

Background: Synonyms:RING finger protein 89, RNF89, TRIM6, tripartite motif containing 6 Background:E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).

Molecular Weight: 40kDa

Gene ID: 117854

UniProt: Q9C030