CEP63 antibody
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- Target See all CEP63 Antibodies
- CEP63 (Centrosomal Protein 63kDa (CEP63))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CEP63 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- centrosomal protein 63kDa
- Isotype
- IgG
- Top Product
- Discover our top product CEP63 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab01606(CEP63 antibody) at dilution of 1:800
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- CEP63 (Centrosomal Protein 63kDa (CEP63))
- Alternative Name
- CEP63 (CEP63 Products)
- Synonyms
- 4921501M07 antibody, AL450317.13gm1 antibody, AW107703 antibody, CD20R antibody, D9Mgc41 antibody, D9Mgc48e antibody, ET2 antibody, zgc:63548 antibody, Cep63-A antibody, Cep63-B antibody, Xcep63 antibody, centrosomal protein 63 antibody, centrosomal protein 63kDa antibody, centrosomal protein 63kDa L homeolog antibody, CEP63 antibody, SYO3AOP1_1060 antibody, Cep63 antibody, cep63 antibody, cep63.L antibody
- Background
- Synonyms: Background:Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152, however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).
- Molecular Weight
- 57-75 kDa
- Gene ID
- 80254
- UniProt
- Q96MT8
- Pathways
- M Phase
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