CAMKK antibody, CAMKKB antibody, 6330570N16Rik antibody, AW061083 antibody, mKIAA0787 antibody, camk2b antibody, fj90d04 antibody, wu:fj90d04 antibody, si:dkey-174n20.2 antibody, CAMKK2 antibody, calcium/calmodulin dependent protein kinase kinase 2 antibody, calcium/calmodulin-dependent protein kinase kinase 2, beta antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase kinase 2 antibody, CAMKK2 antibody, Camkk2 antibody, camk2b1 antibody, CAMK2B antibody, camkk2 antibody
Background
Synonyms:CAMKKB, KIAA0787 Background:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.