CITED2 antibody

Catalog No. ABIN5700517

Product Details anti-CITED2 Antibody

Target: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CITED2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CITED2

Target: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Alternative Name: CITED2 (CITED2 Products)

Synonyms: mrg1 antibody, p35srj antibody, zgc:103418 antibody, CITED2 antibody, cite2 antibody, ASD8 antibody, MRG-1 antibody, MRG1 antibody, P35SRJ antibody, VSD2 antibody, AI835299 antibody, ER154-like antibody, Mrg1 antibody, Msg2 antibody, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 antibody, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 antibody, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 antibody, Cbp/p300-interacting transactivator 2 antibody, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog antibody, cited2 antibody, CITED2 antibody, cite2 antibody, Cited2 antibody, cited2.L antibody

Background: Synonyms:MRG1 Background:Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor, interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis, potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm(LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium(AGP), stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.

Molecular Weight: 24 kDa

Gene ID: 10370

UniProt: Q99967

Pathways: Tube Formation