FBXO7 antibody

Catalog No. ABIN5700866

Product Details anti-FBXO7 Antibody

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunogen: F-box protein 7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab03049(FBXO7 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7 (FBXO7 Products)

Synonyms: fbxo7 antibody, MGC80085 antibody, FBXO7 antibody, fbx7 antibody, MGC135804 antibody, MGC145325 antibody, ATFBP7 antibody, F-BOX PROTEIN 7 antibody, F-box protein 7 antibody, F8K7.20 antibody, F8K7_20 antibody, DKFZp469H0739 antibody, si:ch211-286m4.2 antibody, zgc:114096 antibody, FBX antibody, FBX07 antibody, FBX7 antibody, PARK15 antibody, PKPS antibody, 2410015K21Rik antibody, A230052G17Rik antibody, AI117679 antibody, AW260462 antibody, C85118 antibody, F-box protein 7 antibody, F-box protein 7 L homeolog antibody, FBXO7 antibody, fbxo7.L antibody, fbxo7 antibody, FBP7 antibody, Fbxo7 antibody

Background: Synonyms:FBX7 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.

Molecular Weight: 58.5 kDa

Gene ID: 25793

UniProt: Q9Y3I1