YWHAB antibody

Catalog No. ABIN5701443

Product Details anti-YWHAB Antibody

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YWHAB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Isotype: IgG

Application Details

Application Notes: IHC:1:20-1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Alternative Name: YWHAB (YWHAB Products)

Synonyms: GW128 antibody, HS1 antibody, KCIP-1 antibody, YWHAA antibody, 1300003C17Rik antibody, wu:fb22g04 antibody, wu:fr86a12 antibody, ywhab antibody, ywhab2 antibody, zgc:64092 antibody, 14-3-3beta antibody, fb80c08 antibody, fk41f08 antibody, wu:fb80c08 antibody, wu:fd11d01 antibody, wu:fk41f08 antibody, ywhab1 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a antibody, YWHAB antibody, Ywhab antibody, ywhabb antibody, ywhab.S antibody, ywhab.L antibody, ywhaba antibody

Background: Synonyms:14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB Background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Molecular Weight: 64kDa

Gene ID: 7529

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location