ERLIN1 antibody

Catalog No. ABIN5701549

Product Details anti-ERLIN1 Antibody

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Immunogen: ER lipid raft associated 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

rat pancreas tissue were subjected to SDS PAGE followed by western blot with FNab02848(ERLIN1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ERLIN1

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Alternative Name: ERLIN1 (ERLIN1 Products)

Synonyms: C10orf69 antibody, Erlin-1 antibody, KE04 antibody, KEO4 antibody, SPFH1 antibody, wu:fa10h05 antibody, wu:fb19h05 antibody, zgc:110547 antibody, 2810439N09Rik antibody, C80197 antibody, Keo4 antibody, Spfh1 antibody, RGD1307058 antibody, erlin-1 antibody, ER lipid raft associated 1 antibody, ERLIN1 antibody, erlin1 antibody, Erlin1 antibody

Background: Synonyms:C10orf69, KE04, KEO4, SPFH1 Background:Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

Molecular Weight: 39 kDa

Gene ID: 10613

UniProt: O75477