POLR3K antibody
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- Target See all POLR3K Antibodies
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLR3K antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
- Isotype
- IgG
- Top Product
- Discover our top product POLR3K Primary Antibody
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- Application Notes
- WB : 1:500-1:5000 IHC : 1:20-1:200 IF : 1:50-1:500
- Comment
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Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06634( POLR3K Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- Alternative Name
- POLR3K (POLR3K Products)
- Synonyms
- MGC108467 antibody, POLR3K antibody, 12.3kDa antibody, 1500004O14Rik antibody, AI196849 antibody, AU014893 antibody, C11 antibody, RPC10 antibody, RPC11 antibody, C11-RNP3 antibody, RPC12.5 antibody, hRPC11 antibody, RNA polymerase III subunit K antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, polymerase (RNA) III (DNA directed) polypeptide K antibody, Polr3k antibody, polr3k.S antibody, polr3k antibody, POLR3K antibody
- Background
- Synonyms:C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5 Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
- Gene ID
- 51728
- UniProt
- Q9Y2Y1
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