SOX17 antibody

Catalog No. ABIN5701590

Product Details anti-SOX17 Antibody

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: SRY (sex determining region Y)-box 17

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17 (SOX17 Products)

Synonyms: VUR3 antibody, SOX17 antibody, Sox17alpha antibody, Xsox17 antibody, Xsox17-alpha antibody, Xsox17alpha antibody, sox17-alpha antibody, tSox17alpha antibody, xSox17alpha1 antibody, xSox17alpha2 antibody, xsox17a antibody, sox17 antibody, sox7/17 antibody, Sox antibody, SRY-box 17 antibody, SRY (sex determining region Y)-box 17 antibody, SRY box 17 antibody, SRY-box 17 alpha antibody, sox7/17 protein antibody, SOX17 antibody, sox17 antibody, Sox17 antibody, sox17a antibody, sox7/17 antibody

Background: Synonyms:SOX17, Transcription factor SOX 17 Background:Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells(By similarity).

Gene ID: 64321

UniProt: Q9H6I2