ATG4C antibody
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- Target See all ATG4C Antibodies
- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATG4C antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- ATG4 autophagy related 4 homolog C (S. cerevisiae)
- Isotype
- IgG
- Top Product
- Discover our top product ATG4C Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00675(ATG4C antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
- Alternative Name
- ATG4C (ATG4C Products)
- Synonyms
- apg4c antibody, atg4cl antibody, zgc:86888 antibody, wu:fc56g07 antibody, APG4-C antibody, APG4C antibody, AUTL1 antibody, AUTL3 antibody, Apg4-C antibody, Apg4c antibody, Atg4cl antibody, Autl1 antibody, autophagy related 4C cysteine peptidase antibody, autophagy related 4C, cysteine peptidase antibody, cysteine protease ATG4C antibody, ATG4C antibody, atg4c antibody, Tsp_15996 antibody, Atg4c antibody
- Background
- Synonyms:APG4C, AUTL1, AUTL3 Background:Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Molecular Weight
- 52-55 kDa
- Gene ID
- 84938
- UniProt
- Q96DT6
- Pathways
- Autophagy
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