BBS9 antibody
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- Target See all BBS9 Antibodies
- BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BBS9 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- Bardet-Biedl syndrome 9
- Isotype
- IgG
- Top Product
- Discover our top product BBS9 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00825(BBS9 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
- Alternative Name
- BBS9 (BBS9 Products)
- Synonyms
- b1 antibody, B1 antibody, C18 antibody, D1 antibody, PTHB1 antibody, RGD1308472 antibody, E130103I17Rik antibody, Bardet-Biedl syndrome 9 antibody, bardet-biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 (human) antibody, BBS9 antibody, bbs9 antibody, Bbs9 antibody
- Background
- Synonyms:PTHB1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
- Molecular Weight
- 60 kDa
- Gene ID
- 27241
- UniProt
- Q3SYG4
- Pathways
- Hedgehog Signaling
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